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Poduct Overview

Penicillin-Streptomycin or pen strep 100X Solution is a dual antibiotic solution used as a supplement to cell culture media to control bacterial contamination.

This reagent Solution effective against most gram positive and gram negative bacteria. Penicillin inhibits bacterial cell wall synthesis. Streptomycin inhibits prokaryote protein synthesis.

• Antibiotic solution for the control of bacterial contamination
  
  - Effective against most gram positive and gram negative bacteria

NOTE:

• Most cell culture technologists avoid using antibiotics and antimycotics for routine culture work. Antibiotics and antimycotics may mask contamination by susceptible bacteria and fungi while permitting mycoplasma to flourish unnoticed. Antibiotics and antimycotics may interfere with the metabolism of sensitive cells in culture. However, one may elect to introduce antibiotics and antimycotics for short periods to primary cultures or as a safeguard while propagating specific valuable stocks.
• Applications:
• For reducing the chances of microbial contamination in cell culture. Between 0.5 and 1 mL of Penicillin-Streptomycin solution are added to 100 mL of cell culture media for a final concentration of 50 to 100 I.U./mL penicillin and 50 to 100 (μg/mL) streptomycin.